Richa Priyadarshini | Department of Life Sciences

Profile

Richa
Priyadarshini
Associate Professor
Department of Life Sciences
School of Natural Sciences (SoNS)
218
Block-R- Block, Shiv Nadar University, Shiv Nadar University
Gautam Buddha Nagar Uttar Pradesh
India
Extn: 
220
Profile Summary 

Dr. Richa Priyadarshini is a doctorate from the University of North Dakota, USA where she worked in the lab of Dr. Kevin Young on bacterial cell division. Thereafter, she pursued her post-doctoral research in the lab of Dr. Christine Jacob-Wagner at the Yale University where the focus of her research was bacterial cell morphogenesis. Subsequently, she joined the Forsyth Institute as postdoctoral fellow where the focus of her research was Histone-like protein, HU in Porphyromonas gingivalis. Dr. Priyadarshini has published many papers in leading international journals

Educational Qualifications 
2006
Doctor of Philosophy
University of North Dakota
Work Experience 
20102012
Post-Doctoral Fellow
The Forsyth Institute, Harvard Dental School, Cambridge, MA, USA
20072010
Post-doctoral Associate
Yale University
New Haven, CT, USA
Teaching & Research Interests: 

Research Area: Our lab research work is focused on elucidating the mechanism of cell wall biogenesis and its role in bacterial physiology and diseases. We are working on the following areas:

  1. Bacterial cell wall morphogenesis: One research area my lab is working on is cell division and morphogenesis of bacterial cell using Caulobacter crescentus as a model system. My broad research goal is to uncover the spatio-temporal regulation of cell wall synthesis in bacteria again better understanding of bacterial cell division.
  2. Bacterial Biofilms: Biofilms are known to mediate many diseases, as biofilms shield the bacteria from outside environment making it harder for antibiotics to kill bacterial cells. Our lab is studying the role of cell wall hydrolases in biofilm formation in pathogens such as, E. coli and Staphylococcus aureus.
  3. Microbial biodiversity and beneficial microbes: Currently, we are trying to understand and establish the bacterial communities present in aquatic and soil habitats. We are studying both synergistic and antagonistic microbial interactions in these communities in hope to develop new generation of antimicrobials.

 

Teaching

Undergraduate:

Microbiology (BIO202), Fundamentals of Molecular Biology (BIO206), Scientific Reasoning and Discovery CCC506

Graduate:

Microbial Technology (BIO524)

Conferences (Select): 
  • Richa Priyadarshini, Carla Cugini , Natalia O. Tjokro , Steve D. Goodman and Mary-Ellen Davey. Role of Histone-like protein HU in Porphyromonas ginigvalis. General meeting, American Society for Microbiology, San Fransisco ( June 2012)
  • Richa Priyadarshini, T. Costa, C. Jacobs-Wagner. Assembly of peptidoglycan synthetic machinery in Caulobacter crescentus. 3rd American Society for Microbiology conference on Prokaryotic Development, Cambridge, Massachusetts, 2009.
  • Richa Priyadarshini, M. A. de Pedro, K. D. Young. Division site associated ring-like structures in sacculi purified from Escherichia coli amidase mutants. General meeting, American Society for Microbiology, Orlando, Florida ( May 2006)
  • Richa Priyadarshini and K. D. Young. Role of penicillin binding proteins and amidases in cell separation and chaining in Escherichia coli. Bacteria and Phage Genetics Conference, Madison, Wisconsin (August, 2005)
  • Richa Priyadarshini and K. D. Young. Role of amidases and penicillin binding proteins in cell separation and chaining in Escherichia coli. American Society for Microbiology, Atlanta, (June, 2005)
  • Richa Priyadarshini and K. D. Young. Role of penicillin binding proteins in bacterial cell separation in Escherichia coli. Scholarly Forum, University of North Dakota, Grand Forks (2005)
  • Richa Priyadarshini and K. D. Young. Role of penicillin binding proteins in bacterial cell separation in Escherichia coli. Medicine and Health Sciences, Basic Sciences Retreat. Grand Forks (2004)
  • Richa Priyadarshini and K. D. Young. Role of penicillin binding proteins in bacterial cell separation. American Society for Microbiology, New Orleans. (2004)
Awards(Selected): 
  • Teaching Excellence Award from Shiv Nadar University
  • NSF North Dakota EPSCoR Doctoral Dissertation Grant (research support) for advanced studies and research in bacterial cell separation in E. coli.
  • Selected and funded by the Government of India to be a part of Indian delegation at the 55th Nobel Laureate’s Meeting in Lindau, Germany in 2005.
  • Student Grant Award for Molecular Genetics of Bacteria and Phage Meeting, Madison, Wisconsin (2005) 
  • Student Travel Award by American Society for Microbiology General Meeting (2004)

Scholarly Activity

Journal Articles

  1. Amidase activity is essential for medial localization of AmiC in Caulobacter crescentus. 2017. Dubey A, Priyadarshini R. Curr Genet. Nov 22. doi: 10.1007/s00294-017-0781-9.
  2. Draft Genome Sequence of Deinococcus indicus DR1, a Novel Strain Isolated from a Freshwater Wetland. 2017. Deepika Chauhan, Pulkit Anupam Srivastava, Ragothaman M Yennamalli, and Richa Priyadarshini*. Genome Announc. 2017 Aug 3;5(31). pii: e00754-17. doi: 10.1128/genomeA.00754-17
  3. Graphene Oxide-Coated Surface: Inhibition of Bacterial Biofilm Formation due to Specific Surface–Interface Interactions. 2017. Nisha Yadav, Amrita Dubey, Swapnil Shukla, Chetan Prakash Saini, Govind Gupta, Richa Priyadarshini*, and Bimlesh Lochab*. ACS Omega, 2017, 2 (7), pp 3070–3082
  4. Bacterial contamination of nurses' white coats made from polyester and polyester cotton blend fabrics. 2016. Priyanka Gupta, Nilanjana Bairagi, Richa Priyadarshini, Ashutosh Singh, Deepika Chauhan and Deepti Gupta . Journal of Hospital Infection. DOI information: 10.1016/j.jhin.2016.05.016
  5. Multifunctional reduced graphene oxide coated clothes for oil/water separation and antibacterial application. 2016. Ravi Kant Upadhyay, Amrita Dubey, Prashant R. Waghmare, Richa Priyadarshini, and Susanta Sinha Roy. RSC Adv., 2016, 6, 62760
  6. Bacterial contamination of nurses' white coats after 1st and 2nd shift. 2016. Priyanka Gupta, Nilanjana Bairagi, Richa Priyadarshini, Ashutosh Singh, Deepika Chauhan and Deepti Gupta. Am J Infect Control. 1;45(1):86-88
  7. A biochemical analysis of the interaction of Porphyromonas gingivalis HU PG0121 protein with DNA. 2014. Tjokro NO, Rocco CJ, Richa Priyadarshini, Davey ME, Goodman SD. PLoS One. 28;9(3):e93266. doi: 10.1371/journal.pone.0093266.
  8. The Nucleoid-Associated Protein HU-beta Affects Global Gene Expression in Porphyromonas gingivalis. 2012. Richa Priyadarshini , Carla Cugini , Annette Arndt , Tsute Chen , Natalia O. Tjokro , Steve D. Goodman and Mary-Ellen Davey. Microbiology. Nov22
  9. Osmolality-dependent relocation of penicillin-binding protein PBP2 to the division machinery in Caulobacter crescentus. 2012. Jason Hocking, Richa Priyadarshini, Constantin Takacs, Teresa Costa, Natalie Dye, Lucy Shapiro, Waldemar Vollmer, and Christine Jacobs-Wagner. Journal of Bacteriology 195 (12): 3116-27
  10. HU Protein Affects Transcription of Surface Polysaccharide Synthesis Genes in Porphyromonas gingivalis. 2010. Christine Alberti-Segui, Annette Arndt, Carla Cugini, Richa Priyadarshini and Mary E. Davey. Journal of Bacteriology 192(23):6217-29.
  11. Localization of PBP3 in Caulobacter crescentus is highly dynamic and largely relies on its functional transpeptidase domain. 2008. Teresa Costa, Richa Priyadarshini, and Christine Jacobs-Wagner. Journal of Molecular Microbiology 70(3):634-51.
  12. Role of Peptidoglycan amidases in the development and morphology of the division septum in Escherichia coli.2007. Richa Priyadarshini, Miguel A. de Pedro, and Kevin D. Young. Journal of Bacteriology 189: 5334-5347.
  13. Daughter Cell Separation by penicillin-binding proteins and peptidoglycan amidases in Escherichia coli. 2006. Richa Priyadarshini, David L Popham, and Kevin D. Young. Journal of Bacteriology 188: 5345-5355.
  14. Endopeptidase penicillin-binding proteins 4 and 7 play auxiliary roles in determining uniform morphology of Escherichia coli. 2004. Bernadette M. Meberg, Avery L. Paulson, Richa Priyadarshini, and Kevin D. Young. Journal of Bacteriology 186: 8326-8336.